Jon Cryer Charlie Sheen were the heart of Two and a Half Men, one of the highest-rated comedies in television history. At its peak, the show attracted over 15 million viewers per episode.

In March 2011, Warner Bros. fired Charlie Sheen after weeks of erratic public behavior and a feud with creator Chuck Lorre. It was one of the most dramatic departures in TV history.

Ashton Kutcher replaced Sheen on the show, but fans felt the magic of the original pairing was gone. Cryer stayed and earned two Emmy Awards, keeping the show alive through the transition.

Cryer calls it a complicated relationship. He's no longer angry, but the two former co-stars still don't talk. The legacy of their partnership, however, lives on in reruns watched worldwide.