What Happened To Katherine Heigl — From Emmy-winning Grey's Anatomy star to a "difficult" label and a Netflix comeback — here is the full Katherine Heigl story.

As Dr. Izzie Stevens, Katherine Heigl became a breakout star and won a Primetime Emmy in 2007.

Knocked Up, 27 Dresses, The Ugly Truth — for a few years, Katherine Heigl was the queen of the rom-com.

Candid 2008 comments about Knocked Up and a withdrawn Emmy nomination sparked a "difficult" narrative that stuck.

Katherine Heigl left Grey's Anatomy in 2010 and leaned into family life on a ranch out West.